LibGuides: Problem-based Learning & Finding the Evidence: Current Case

Books

WHO consolidated guidelines on tuberculosis
Publication Date: 2020
Chapters include: Standard treatment regimens -- Monitoring during treatment -- Co-management of HIV and active TB disease -- Supervision and patient support.
Sepsis management in resource-limited settings by Arjen M. Dondorp, et al.
Publication Date: 2019
Sepsis management : PIRO and MODS by Jordi Rello, et al
Chapters include: Multiorgan Dysfunction Syndrome (MODS): What is New? -- MODS Scores: Which One Should I Use? -- PIRO Concept and Clinical Failure -- PIRO-Based Approach for Sepsis in Immunocompromised Patients: What's Different?

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Sebastian Moreira -- View from Maputo

The Point of Care tools will be very helpful in clarifying aspects of the case. Many of these POC tools also reference the latest guidelines.

Don't forget the Drug Information Resources for gaining a better understanding of the drugs involved in this week's case.

Resources for this Case

Textbooks (look left)

Point of Care Tools

National & International Organizations

Lumbar Puncture - Video Demonstration

Mozambique

PubMed Searches - Reminders

Advice from Dr. Marsh

Point of Care Tools

Point of Care Tools

All of the tools have some great information on this topic. However, each has some special features that highlight information in different ways. Check out the details on topics like systemic inflammatory response syndrome. However, the textbooks & journals might be a quicker look up for some topics like early goal directed therapy.

Medscape
The HIV section has a variety of good information, including a pathophysiology section with a list of opportunistic infections. Short and to the point.If you haven't used this one before, sign up for the free account to use this tool.
Up to Date
It has an approach to the immunocompromised patient with fever and pulmonary infiltrates
Micromedex
Check out the drug info they have for either HIV/AIDS or TB.

National & International Organizations

National & International Organizations

Including the links from the resource page posted on the meded-portal.

WHO Hiv - AIDS Information
WHO Guidelines on Treating & Preventing HIV Infection
WHO - TB Information & FactSheets
WHO Country Page for Mozambique
Be sure to use the GMO link for more details.
CDC: HIV page
CDC Tuberculosis Page
NIH Guidelines for ARV Treatment of HIV & Patients
TRIP Database: Search for Guidelines
Once you do your search, use the filters on the left to limit to just guidelines
HIV InSite (UCSF)
Has comprehensive guidelines to HIV/AIDS prevention & treatments.
Updated: Aids Info & Prenatal Care
Check out the recent changes (as of January, 2023) or download the guidelines.

Lumbar Puncture Procedure Videos

NEJM lumbar puncture video

Mozambique & Maputo Resources

Maputo Formulary. 2020
Maputo Medical Resources List 2017
Geographic accessibility to primary healthcare centers in Mozambique
A research article that takes advantage of GIS to map healthcare resources in the country.
USAID on Mozambique
International Trade Association: Mozambique Healthcare
Healthcare in Mozambique (Wikipedia)

PubMed Search Tips

PubMed Tips

From early goal directed therapy to HAART to HIV treatment in Africa - PubMed will have a number of resources for the topic at hand. Here are a few reminders of some of the PubMed search tips you might have encountered over the last 2 years.

Title Search - if your search term is in the title, you can be pretty sure it is on topic. Remember how to do that? It might help with a search like early goal directed therapy.
Use filters - in some situations a limit for Language, age, or publication type can help you cut through the results.
Problems with abbreviations? - PubMed likes things spelled out.
More like the one I have - use similar articles link.

PubMed
Covers over 5,600 journals in the biomedical and health sciences and years covered are generally 1946 - present.. Search using keywords, be as specific as possible. See UC San Diego Library's PubMed page.
Full-text access in Mozambique: HINARI
If you were in Mozambique, you might not have the vast resources of UCSD's full-text access. What would you do? HINARI is one program that will help provide much broader access to full-text from a PubMed search.
African Index Medicus
An international index to African health literature and information sources with an emphasis on regional or country journals pubished in Africa. It is multi-lingual as well.

Advice from Dr. Marsh

Dr. Marsh encourages the groups he facilitates to scan the New England Journal of Medicine weekly. It is a habit he started years ago and continues even now. There have frequently been articles pertinent to the weekly cases, and in 2013, it was very pertinent to this case. The March 7, 2013 issue has some related articles:

Reminders of Resources

A Reminder About Resources