Organic Chemistry: SciFinder-n

New Features (click the icon for an example)

Retrosynthesis Planner: Generate a full retrosynthetic analysis of all known synthetic routes for a given molecule; organize into easy to navigate synthetic plans; and access commercial source availability and pricing.
 

PatentPak: Full-text searching of 18 million patents, with chemical substances marked so they can be easily found within the patent.
 

Additional Enhancements

• “Search All” to search across the substance, reaction, and references databases.
• Familiar searching options: booleans, truncation/wildcards, parentheses, e.g. (flavor OR odor) AND menthol.
• Combined keyword and structure searching.
• An option to exclude particular results from searches.
• Autosuggesting search terms.
• Relevancy-based sorting of results now the default.
• Reaction search results grouped by scheme (same reactants and products).
• Live History – edit and rerun past searches.
• Additional filter functionality in the results: setting publication date ranges, searching within the filter categories along with frequency and natural order, substance role filter if chemical included in reference searches.
• Clearer labeling to connect you to full-text articles, now with UC-eLinks included in the options.
• Citation mapping to quickly see cited and citing articles.
• Improvements in combined search functionality: two authors, author(s)/journal, author(s)/organization, two substance property data points.
• Easy to keep up with new releases of SciFinder-n and get help from the account page.
• Automatic deduping of CAS/Medline records (coming later this summer).
• Ability to have multiple tabs running without getting kicked out of sessions.

You can search for substances in SciFinder by

• Name and/or CAS Registry Number, using the Substances search
• Molecular Formula
• Structure or Substructure. SciFinder has its own structure editor, but you import .mol files or draw your structure in ChemDraw and launch SciFinder from there..

From the CAS Registry record, view:

• Other names and identifiers
• Data
  • Experimental property data, with associated article references in SciFinder.
  • Experimental spectra, either actual spectra from companies like Bio-Rad, or references to articles.
  • Predicted properties and spectra
• Regulatory information

And get links to retrieve:

• References to journal articles, patents and other documents, limited by subcategories (crystal structure, preparation, analytical study, etc).
• Commercial suppliers for the substance.
• Reactions, limited by one or more roles (product, reagent, etc.)

Reaction searching can be done in SciFinder by:

• From a substance record, go to Reactions, and select which role(s) for your substance from the filters to the left.
• Use the structure editor to draw the reaction, import the reaction structures from ChemDraw, or launch the SciFinder search from ChemDraw. You can run the search on the structures exactly as drawn or broaden to a substructure search.

Reactions can also be searched as a research topic, which will give you references as results, rather than reactions.

Reaction results can be filtered by reaction details (reagent, solvent, catalyst, yield, steps, reaction classification, non-participating functional groups) or publication details like journal title and publication year.

Each reaction includes reaction details (reagents, solvents, steps/stages, etc.) and a link to the associated reference to a journal article, patent, or other source. Click on View Reaction Detail for more information about the reaction from MethodsNow. For drawn reactions, you may be able to filter by similarity.