| COSSAP | Comprehensive Opioid, Stimulant, and Substance Abuse Program | changed to COSSUP - Comprehensive Opioid, Stimulant, and Substance Use Program |
| CPO | Coral Protocols Online | unable to verify |
| DBSVB | Developmental Biology and Structural Variation Branch | changed to DBCAB - Developmental Biology and Congenital Anomalies Branch |
| ECT | Employment Cost Trends | replaced by ECI - Employment Cost Index |
| HCRL | Horticultural Crops Research Laboratory | unable to verify |
| HCRU | Horticultural Crops Research Unit | unable to verify; likely changed to Horticultural Crops Production and Genetic Improvement Research Unit (no acronym) |
| LPCS | Land Product Characterization System | unable to verify |
| MAT | Medication-Assisted Treatment | unable to verify |
| OHSN | Occupational Health Safety Network | retired 9/19 |
| QART | Quality Assessment Reporting Tool | certificate error |
| WIP | Weatherization and Intergovernmental Programs Office | unable to verify |
