| AMPD | Air Markets Program Data | changed to CAMPD - Clean Air Markets Program Data |
| ASPR | Assistant Secretary for Strategic Preparedness and Response | changed to Administration for Strategic Preparedness and Response (same acronym) |
| BIDS | Biomedical Informatics and Data Science | changed to BACS - Bioinformatics and Computational Science |
| ES | Energy Systems | split into TAPS (Transportation and Power Systems) and ESIA (Energy Systems and Infrastructure Analysis) |
| IAO | Interagency Office | unable to verify |
| NESDOCS | NESDIS Directives Online Collaboration System | changed to NESDIS Policies, Procedures, and Plans (no acronym) |
| PAIR | Patent Application Information Retrieval | retired 7/31/22; replaced by Patent Center |
