| GPO |
Government Pension Offset | Government Publishing Office (formerly Government Printing Office) |
| GPOI |
Global Peace Operations Initiative (older link archive; archive2; archive3) |
| GPP |
Green Parks Plan | Green Power Partnership |
| GPRA |
Government Performance and Results Act |
| GPS |
Geographic Profile of Employment and Unemployment (older link archive) | Global Positioning System | Office of Global Publishing Solutions (older link archive) |
| GPSN |
Global Patent Search Network (unable to verify 2/17) |
| GRACE |
Gravity Recovery & Climate Experiment |
| GRACEnet |
Greenhouse gas Reduction through Agricultural Carbon Enhancement network (older link archive) |
| GRAIL |
Gravity Recovery and Interior Laboratory |
| GRAS |
Generally Recognized as Safe (older link archive) |
| GRD |
Geologic Resources Division |
| G.R.E.A.T. |
Gang Resistance Education And Training Program (unable to verify 8/17) |
| GRIN |
Germplasm Resources Information Network |
| GRIP |
Genesis and Rapid Intensification Processes (older link archive) |
| GRP |
Grassland Reserve Program |
| GRTS |
Grants Reporting and Tracking System |
| GSA |
General Services Administration (older link archive) |
| GSAM |
General Services Acquisition Manual (older link archive) |
| GSD |
Global Systems Division |
| GSFC |
Goddard Space Flight Center (older link archive) |
| GSM-102 |
Export Credit Guarantee Program |
| GSO |
Government to Government Services Online |
| GSOD |
Global Summary of the Day (older link archive) |
| GSS |
Database of Genome Survey Sequences (merged into Nucleotide) | Global Security Sciences (unable to verify 6/19) |
| GSTC |
Geospatial Service and Technology Center (changed to GTAC) |
| GTAC |
Geospatial Technology and Applications Center |
| GTB |
Genome Technology Branch (defunct) |
| G/TIP |
Office to Monitor and Combat Trafficking in Persons (changed to TIP Office) |
| GTM |
Bureau of Global Talent Management |
| GTMBA |
Global Tropical Moored Buoy Array |
| GTO |
Geothermal Technologies Office |
| GTP |
Geothermal Technologies Program (changed to GTO) |
| GTR |
Genetic Testing Registry |
| GTSSData |
Global Tobacco Surveillance System Data |
| GUDID |
Global Unique Device Identification Database (older link archive) |
| GUPCP |
Geographically Updated Population Certification Program (unable to verify 7/20) |
| GusNIP |
Gus Schumacher Nutrition Incentive Program |
| GVP |
Global Volcanism Program |
| GWA |
Governmentwide Accounting & Reporting Modernization (changed to CARS) |
| GWEP |
Geriatrics Workforce Enhancement Program |
| GwoB |
Government Without Boundaries (defunct) |