| USDA |
United States Department of Agriculture |
| USDFRC |
U.S. Dairy Forage Research Center |
| USDS |
United States Digital Service |
| USEER |
U.S. Energy and Employment Report |
| USEITI |
United States Extractive Industries Transparency Initiative (older link archive) |
| USES |
United States Employment Service (defunct) |
| USFA |
U.S. Fire Administration |
| USGCRP |
U.S. Global Change Research Program |
| USGEO |
U.S. Group on Earth Observations (defunct or inactive 1/17, WH transition) |
| USGS |
United States Geological Survey |
| USHCN |
U.S. Historical Climatology Network |
| USHIK |
United States Health Information Knowledgebase |
| USHMC |
U.S. Housing Market Conditions |
| USHMM |
United States Holocaust Memorial Museum |
| USIA |
United States Information Agency (changed to IIP) |
| USIBWC |
U.S. Section of the International Boundary and Water Commission |
| USICH |
United States Interagency Council on Homelessness |
| USICN |
U.S. International Competition Network (unable to verify 9/16) |
| USINT |
U.S. Interests Section (replaced by U.S. Embassy Cuba; see archive) |
| USIP |
United States Institute of Peace |
| USITC |
United States International Trade Commission |
| USJC |
Judicial Conference of the United States |